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The fact that diarrhea is the second leading cause of preventable death in children under the age of five in developing countries is well known. Yet, the question remains: What can be done? Here, we present a few of our own theories and catalogue those of other key advocates. We hope this sheds some light on how we at LifeDrops seek to address this complex issue.


Developing WorldLifeDrops Executive Summary

Ian Matthews, LiveLeaf

In depth program overview outlining clinical work, partnership strategy and impact measurement.




liveleaf_lifedrops_programSummary of LifeDrops Program and Partnership Benefits

Ian Matthews, LiveLeaf

Summary of the need for the LifeDrops program and its benefits.




Matthews, I., LiveLeaf Inc. May 2014

An overview of current systems for the distribution of healthcare products in low and middle income countries.



LiveLeaf Use of Reactive Plant ImmunityUse of Reactive Plant Immunity to address symptoms associated with acute diarrhea in children from resource-poor communities

Lawson, T. et. al., LiveLeaf, Inc.

LifeDrops science and clinical overview



Antimicrobial Resistance ReportAntimicrobial Resistance – Global Report on surveillance

World Health Organization, 2014

WHO sounds the alarm on antimicrobial resistance with a particular focus on antibiotics used to treat dysentery calling it a global health security emergency.



Treatment of DiarrheaTreatment of diarrhea in young children: Results from surveys on the perception and use of oral rehydration solutions, antibiotics, and other therapies in India and Kenya

Zwisler, G. et al., Journal of Global Health, 3 (1), June 2013

Caregivers primary treatment goal is to stop diarrhea, and many believe that antibiotics or ORS will accomplish this goal. Inappropriate treatment and especially overuse of antibiotics is common. The results provide valuable insight into health-seeking behaviors and suggest significant opportunities to enhance treatment.




pneumonia and diarrheaPneumonia and diarrhea Tackling the deadliest diseases for the world’s poorest children

Unicef, June 2012

Instrumental in re-focusing effort and donor dollars on the two most common killers of children under five years old.




Linking nutrition and healthLinking Nutrition and Health: Progress and Opportunities

Bread for the World Institute, Briefing Paper Number 14, February 2012

Improving investments in nutrition programming by linking nutrition, health and agriculture sectors. Details the important role that diarrhea plays in undermining child nutritional development.




progress in control of diarrheaProgress and barriers for the control of diarrhoeal disease

Santosham, M. et al., The Lancet 376 (9734), July 2010

Understanding the barriers to adoption and scaling of new treatments for diarrhea.




Diarrhea: Why children are still dying and what can be donediarrhea in children

Unicef and World Health Organization, 2009

Groundbreaking report on the devastating effects of diarrhea on children under five years old in the developing world.




malnutrition effectsMalnutrition as an enteric infectious disease with long-term effects on child development

Guerrant, R. et al., Nutrition Reviews, 66(9) September, 2008

Meta-analysis of clinical data related to the malnutrition-diarrhea cycle and its implications for childhood development and novel interventions.

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